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Danocrine (Danazol)

No Prescription Meds

Home » Pain Medicine » Danocrine (Danazol)

Danocrine (Danazol) is a synthetic steroid used to treat endometriosis and fibrocystic breast disease. It may also be used to treat excessive menstrual bleeding.

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About Danocrine (Danazol):

Product Type: Pain Medicine

Brand name: Danocrine Generic name: Danazol Classification: Synthetic androgen (gonadotropin inhibitor) Action/Kinetics: Inhibits the release of gonadotropins (FSH and LH) by the anterior pituitary; thus inhibits synthesis of sex steroids and competitively inhibits binding of steroids to their cytoplasmic receptors in target tissues. In women this action arrests ovarian function induces amenorrhea and causes atrophy of normal and ectopic endometrial tissue. Has weak androgenic effects. Onset fibrocystic disease: 4 weeks. Time to peak effect amenorrhea and anovulation: 6-8 weeks; fibrocystic disease: 2-3 months to eliminate breast pain and tenderness and 4-6 months for elimination of nodules. t 1/2: 4.5 hr. Duration: Ovulation and cyclic bleeding usually resume 60-90 days after cessation of therapy. Uses: Endometriosis amenable to hormonal management in clients who cannot tolerate or who have not responded to other drug therapy. Fibrocystic breast disease. Hereditary angioedema in males and females. Investigational: Gynecomastia menorrhagia precocious puberty idiopathic immune thrombocytopenia lupus-associated thrombocytopenia and autoimmune hemolytic anemia. Contraindications: Undiagnosed genital bleeding; markedly impaired hepatic renal and cardiac function; pregnancy and lactation. Special Concerns: Use with caution in children treated for hereditary angioedema due to the possibility of virilization in females and precocious sexual development in males. Use with caution in conditions aggravated by fluid retention (e.g. epilepsy migraine cardiac or renal dysfunction). Geriatric clients may have an increased risk of prostatic hypertrophy or prostatic carcinoma. Side Effects: Androgenic: Acne decrease in breast size oily hair and skin weight gain deepening of voice and hair growth clitoral hypertrophy testicular atrophy. Estrogen deficiency: Flushing sweating vaginitis nervousness changes in emotions. GI: N&V constipation gastroenteritis. Hepatic: Jaundice dysfunction. CNS: Fatigue tremor headache dizziness sleep problems paresthesia of extremities anxiety depression appetite changes. Musculoskeletal: Muscle cramps or spasms joint swelling or lock-up pain in back legs or neck. Miscellaneous: Allergic reactions (skin rashes and rarely nasal congestion) hematuria increased BP chills pelvic pain carpal tunnel syndrome hair loss change in libido. Drug Interactions: Insulin / Insulin requirements Warfarin / PT in warfarin-stabilized clients How Supplied: Capsule: 50 mg 100 mg 200 mg

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No Prescription Meds: This is your Albany on drugs: New legislation would hike cost of mail-order meds. Whenever state lawmakers mess around with the rules for health insurance, New Yorkers should hang on to their wallets. The latest scheme out of the Legislature - meant to squash the growing use of mail-order pharmacies - is no exception. This proposed law does nothing to improve the quality or quantity of the drugs that people will get. But - like most of Albany's ill-conceived mandates - it will mean higher prices. Directly, the law actually bans discounts for customers who buy medications via mail order. Indirectly, the mandate is almost certain to drive up premiums for businesses that are already struggling to afford coverage for their employees. The result could easily be more people who lack any drug coverage at all. Yet this legislation - co-sponsored by Bronx Assemblyman Carl Heastie and Buffalo-area Sen. George Maziarz - whizzed through the Legislature with just four "no" votes. Which leaves Gov. Cuomo and his veto pen as the last line of defense for beleaguered consumers. More and more health plans are pushing their customers to use mail-order pharmacies for reasons that will be obvious to anyone who shops online: It's cheaper. The mail-order medication dealers handle huge volumes, which means economies of scale and special discounts from manufacturers. They're highly automated and centralized. And they operate with none of the overhead that goes along with operating millions of storefronts.